Gene interactions and pathways from curated databases and text-mining

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APP — GFAP

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Kwak et al., Biochem Biophys Res Commun 2006 : Overexpressed APP enhanced GFAP promoter activity and expression of GFAP, while gene silencing of APP by RNA interference decreased GFAP expression
Kwak et al., Neurotox Res 2010 : Application of small interference RNA ( siRNA ) for STAT3 suppressed GFAP expression even in the presence of APP