Gene interactions and pathways from curated databases and text-mining

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GJC3 — MAPK6

Text-mined interactions from Literome

Hossain et al., J Cell Physiol 1999 : Since many of these agents activate additional protein kinases, our present study examined whether activation of MAPK was sufficient for Cx43 phosphorylation and GJC blockade ... Taken together, our results suggest that disruption of GJC is not solely mediated by either activated MAPK or Cx43 phosphorylation but requires the participation of additional kinases and regulatory components
Lin et al., J Cell Biol 2001 : Furthermore, we did not find evidence for a role for mitogen activated protein kinase in mediating the disruption of GJC by v-Src
Lin et al., Cell communication & adhesion 2006 (Cell Transformation, Neoplastic) : Cells coexpressing v-Src and the triple serine to alanine mutant, Cx43S255/279/282A, confirmed that mitogen activated protein ( MAP ) kinase phosphorylation of Cx43 was not required for v-Src induced disruption of GJC and that tyrosine phosphorylation was sufficient