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GP9 — RELA

Text-mined interactions from Literome

D'Addario et al., J Mol Biol 2001 : To our knowledge this is the first report showing that the binding of a herpesvirus envelope glycoprotein to CR2 on human B cells results in the activation of the NF-kappaB transcription factor leading to the upregulation of IL-6 gene expression in these lymphocytes
Bentires-Alj et al., Oncogene 2003 (Colonic Neoplasms) : Indeed, the inhibition of NF-kappaB reduced mdr1 mRNA and P-glycoprotein expression in HCT15 cells
Lee et al., Cancer Chemother Pharmacol 2004 : As expected, SNL glycoprotein dose-dependently inhibited PKCalpha translocation, NF-kappaB DNA binding activity, NF-kappaB protein activity and NO production in HCT-116 cells stimulated with TPA ( 61.68 ng/ml, 100 nM )
Heo et al., Toxicol In Vitro 2004 (Breast Neoplasms) : To test the effect of SNL glycoprotein on the DNA binding activities of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1), and nitric oxide ( NO ) production, these experiments were carried out using electrophoretic mobility shift assays ( EMSA ), western blot analysis, and the Griess method ... Results in this experiment showed that SNL glycoprotein inhibits 12-O-Tetra decanoylphorbol-13-acetate ( TPA ; 100 nM ) -induced DNA binding activities of NF-kappaB and AP-1, and enhances NO production in MCF-7 cells
Ko et al., Toxicol In Vitro 2005 : We also demonstrated that RVS glycoprotein inhibits activities of the nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) induced by G/GO, and prevents from G/GO induced apoptosis in the NIH/3T3 cells
Heo et al., J Med Food 2005 : The results in this study indicated that SNL glycoprotein induces apoptosis through modulation of PKCalpha and NF-kappaB activity in MCF-7 cells ... In fact, SNL glycoprotein interfered with PKCalpha membrane translocation and inhibited NF-kappaB ( p50 ) protein activity in MCF-7 cells stimulated with TPA ( 61.68 ng/mL, 100 nM ) dose-dependently
Lim et al., J Med Food 2005 : Taken together, the results of this study showed that the activation of PKCalpha, NF-kappaB , and Bax expression by SNL glycoprotein is possibly involved in the apoptotic process
Deepak et al., Biochimie 2006 (Carcinoma, Ehrlich Tumor...) : Antiangiogenic and proapoptotic activity of a novel glycoprotein from U. indica is mediated by NF-kappaB and Caspase activated DNase in ascites tumor model
Lee et al., Food Chem Toxicol 2007 (Colitis) : In addition, the results obtained from electrophoretic mobility shift assay ( EMSA ) and western blot analysis showed that UDN glycoprotein dose-dependently inhibits DNA binding activity of nuclear factor-kappa B (NF-kappaB) , and activities of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and manganese-superoxide dismutases ( Mn-SOD ) in LPS stimulated RAW 264.7 cells
Lee et al., Cancer Lett 2007 (Colonic Neoplasms) : The results obtained from electrophoretic mobility shift assay ( EMSA ) and Western blot analysis showed that UDN glycoprotein blocks the DNA binding activities of nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1), and attenuates the activities of NF-kappaB subunits ( p50 and p65 ), and AP-1 subunits ( c-Jun and c-Fos ), respectively
Lee et al., J Nutr Biochem 2008 (Carcinoma, Hepatocellular...) : In nuclear factor-kappa B (NF-kappaB) mediated apoptosis pathway, the results showed that SNL glycoprotein dose-dependently blocked DNA binding activity of NF-kappaB , activity of inducible nitric oxide synthase (iNOS) and production of inducible nitric oxide ( NO )
Lee et al., Toxicol Appl Pharmacol 2007 (Colonic Neoplasms...) : Also, 0.02 % UDN glycoprotein suppressed the DNA binding activities of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1), accompanying the inhibitions of its subunits ( p50, p65, c-Jun, and c-Fos ), pro-inflammatory proteins [ inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) ], and pro-inflammatory cytokines [ tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 ] on DMH stimulated ACF formation
Hartz et al., FASEB J 2008 : Inhibition of JNK, but not NF-kappaB , blocked DEP induced P-glycoprotein up-regulation, indicating a role for AP-1 in the signaling pathway
Yurochko et al., J Virol 1997 : The human cytomegalovirus UL55 ( gB ) and UL75 ( gH ) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection
Mejdoubi et al., Biochem Biophys Res Commun 1999 : NF-kappaB is involved in the induction of the rat hepatic alpha1-acid glycoprotein gene by phenobarbital