Gene interactions and pathways from curated databases and text-mining

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HDAC11 — IL8

Text-mined interactions from Literome

Gilmour et al., Am J Physiol Lung Cell Mol Physiol 2003 : PM ( 10 ) and H ( 2 ) O ( 2 ) increased IL-8 protein release from A549 cells after 24-h treatment, and this was enhanced by histone deacetylase inhibition by trichostatin A ( cotreatment )
Chavey et al., Mol Pharmacol 2008 (Breast Neoplasms) : In addition, blocking NF-kappaB pathway by adenoviral delivery of a dominant negative IkappaBorIkappaB kinase complex 2 (IKK2) mutant abolished IL-8 gene induction by histone deacetylase inhibitors
Rehni et al., Naunyn Schmiedebergs Arch Pharmacol 2012 (Opioid-Related Disorders...) : The present study has been designed to investigate the effect of selective inhibitors of histone deacetylase and/or N-acetyl-Asp-Glu-Val-Asp-al ( Ac-DEVD-CHO ), a selective interleukin-1ß converting enzyme inhibitor , on the development of naloxone induced opioid withdrawal syndrome both in vitro and in vivo and the effect of histone deacetylase inhibition on histone H3 acetylation in brain
Venza et al., Pigment Cell Melanoma Res 2013 (Melanoma...) : Here, we explored the effects of the novel class II-specific histone deacetylase inhibitors ( HDACis ) MC1568 and MC1575 on interleukin-8 (IL-8) expression and cell proliferation in cutaneous melanoma cell line GR-M and uveal melanoma cell line OCM-3 upon stimulation with phorbol 12-myristate 13-acetate ( PMA )