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HDAC2 — IL6

Text-mined interactions from Literome

Frost et al., Am J Physiol Endocrinol Metab 2004 : Optimal IL-6 synthesis may require both stress kinase and histone deacetylase activity
Mantovani et al., Vascul Pharmacol 2006 (Cardiovascular Diseases...) : CRP and SAP are produced primarily in the liver in response to IL-6 , while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor ( TLR ) engagement
Chokas et al., J Biol Chem 2010 (Hyperoxia) : Importantly, we show in vivo that Foxp1 and HDAC2 act cooperatively to regulate expression of the cytoprotective cytokine interleukin-6 , which results in increased resistance to hyperoxic lung injury in Foxp1/HDAC2 compound mutant animals
Pietrella et al., Infect Immun 2010 (Inflammation) : In particular Sap1, Sap2 , and Sap6 significantly induced interleukin-1ß (IL-1ß), tumor necrosis factor alpha ( TNF-a ), and IL-6 production
Garlanda et al., Curr Pharm Des 2011 (Atherosclerosis...) : CRP and SAP are produced primarily in the liver in response to IL-6 , while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor ( TLR ) engagement
Rehni et al., Naunyn Schmiedebergs Arch Pharmacol 2012 (Opioid-Related Disorders...) : The present study has been designed to investigate the effect of selective inhibitors of histone deacetylase and/or N-acetyl-Asp-Glu-Val-Asp-al ( Ac-DEVD-CHO ), a selective interleukin-1ß converting enzyme inhibitor , on the development of naloxone induced opioid withdrawal syndrome both in vitro and in vivo and the effect of histone deacetylase inhibition on histone H3 acetylation in brain
Vitoriano-Souza et al., PloS one 2012 : With regard to cytokines, the SAP led to production of interleukin (IL)-2, IL-6 , and IL-4
Liu et al., Journal of inflammation (London, England) 2013 : In addition, HDAC inhibitors significantly inhibited poly ( I:C ) -induced IL-6 production in both of the epithelial cells
Ku et al., Cytokine 1993 (Carcinoma, Hepatocellular...) : By contrast, gene expression of the major APR of the mouse, serum amyloid P-component (SAP) , a structural homologue of CRP, increased in response to either IL-1 or IL-6 under the same conditions