Gene interactions and pathways from curated databases and text-mining

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AKT3 — HK3

Text-mined interactions from Literome

Gottlob et al., Genes Dev 2001 : First, Akt increases mitochondria associated hexokinase activity
Wang et al., Neurosci Lett 2008 : The hypothesis that neurotrophic factor dependent activation of Akt would regulate hexokinase association with the mitochondria was tested and quantitative Western blotting showed no effect of blockade of the phosphoinositide 3-kinase ( PI 3-kinase ) /Akt pathway using the inhibitor LY294002, indicating this interaction of hexokinase with mitochondria was not neurotrophic factor or Akt dependent