Gene interactions and pathways from curated databases and text-mining

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HNF1B — MAPK12

Text-mined interactions from Literome

Yosimichi et al., Eur J Biochem 2001 : These inhibitors of MAPKK and MAPK suppressed phosphorylation of ets-like gene-1 (Elk-1) and nuclear activating transcription factor-2 ( Atf-2 ) induced by CTGF/Hcs24 in a dose dependent manner, respectively
Faour et al., J Biol Chem 2005 (Arthritis, Rheumatoid) : Initial studies confirmed that PGE2 induces egr-1 mRNA expression and protein synthesis by restricted SAPK2/p38 MAPK dependent activating transcription factor-2 ( ATF-2) dimer transactivation of the egr-1 promoter as judged by studies using wild-type ( WT ) and deletion mutant egr-1 promoter constructs, Northern and Western blotting, and standard and supershift electrophoretic mobility shift analyses
Tancharoen et al., J Immunol 2005 (MAP Kinase Signaling System) : The kinase inhibitor profile on the RgpB-neuropeptide release from HPC revealed a new PAR-2 signaling pathway that was mediated by p38 MAPK and activated transcription factor-2 activation, in addition to the PAR-2-p44/42 p38MAPK and -AP-1 pathway
Si et al., J Virol 2005 : JNK1/2 inhibitors reduced CVB3 induced phosphorylation of activating transcription factor 2 , and the p38 MAPK inhibitor reduced CVB3 induced phosphorylation of heat shock protein 27
Hisatsune et al., J Immunol 2008 : Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2 , cAMP response element binding protein, and NF-kappaB activation
Cho et al., Mol Endocrinol 2009 : The inhibition of MAPK dependent activating transcription factor 2/c-Jun phosphorylation by GR in COX-2 repression was a result of MAPK phosphatase-1 (MKP-1) induction