Gene interactions and pathways from curated databases and text-mining

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IFNA1 — MAPK14

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: MAPK14 → IFNA1 (increases)
    Evidence: We determined whether p38 MAPK is activated by IFN-alpha in BCR-ABL-expressing cells and whether its function is required for the generation of growth inhibitory responses. IFN-alpha treatment induced phosphorylation/activation of p38 in the IFN-alpha-sensitive KT-1 cell line, but not in IFN-alpha-resistant K562 cells.