Gene interactions and pathways from curated databases and text-mining

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IGFBP3 — VEGFA

Text-mined interactions from Literome

Dahlfors et al., Endocrinology 2000 : In conclusion, vascular endothelial growth factor and transforming growth factor-beta1 regulate IGFBP expression in bovine aortic endothelial cells
Liu et al., Oncogene 2007 (Neovascularization, Pathologic...) : In vitro, IGFBP-3 inhibited both vascular endothelial growth factor- and IGF stimulated human umbilical vein endothelial cells vascular network formation in a matrigel assay
Oh et al., Cancer Sci 2012 (Carcinoma, Squamous Cell...) : IGFBP-3-GGG , a mutant IGFBP-3 with loss of IGF binding capacity, suppressed VEGF production ... In addition, we found that IGFBP-3 suppressed VEGF expression, even in mouse embryonic fibroblasts from an IGF-1R-null mouse