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FOS — IL17A
Text-mined interactions from Literome
Benderdour et al., J Rheumatol 2002
(Osteoarthritis) :
Of note, in OA chondrocytes,
IL-17 and IL-1beta
induced collagenase-3 production through
AP-1 occurred with differential protein complexes : IL-17 stimulation resulted in FosB activation, while IL-1beta stimulated c-Fos ... We demonstrated that
IL-17 and IL-1beta
induced collagenase-3 production in OA chondrocytes mainly through
AP-1 mediated transcriptional activity but with differential protein complexes, suggesting that some AP-1 proteins play a pivotal role in the different cytokine responses in terms of collagenase-3 production
Tucci et al., Br J Haematol 2013
(Bone Resorption...) :
These cells showed increased RNA transcription of genes enrolled in the maturation of OCs, while NFATC1 and
FOS were
induced by
IL17A , independently of NFKB1 phosphorylation