Gene interactions and pathways from curated databases and text-mining

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FOS — IL17A

Text-mined interactions from Literome

Benderdour et al., J Rheumatol 2002 (Osteoarthritis) : Of note, in OA chondrocytes, IL-17 and IL-1beta induced collagenase-3 production through AP-1 occurred with differential protein complexes : IL-17 stimulation resulted in FosB activation, while IL-1beta stimulated c-Fos ... We demonstrated that IL-17 and IL-1beta induced collagenase-3 production in OA chondrocytes mainly through AP-1 mediated transcriptional activity but with differential protein complexes, suggesting that some AP-1 proteins play a pivotal role in the different cytokine responses in terms of collagenase-3 production
Tucci et al., Br J Haematol 2013 (Bone Resorption...) : These cells showed increased RNA transcription of genes enrolled in the maturation of OCs, while NFATC1 and FOS were induced by IL17A , independently of NFKB1 phosphorylation