Gene interactions and pathways from curated databases and text-mining

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IL2RA — IL8

Text-mined interactions from Literome

Kaminska et al., Tumour Biol 2005 (Colorectal Neoplasms) : The levels of circulating interleukin (IL)-6, IL-8 , macrophage colony stimulating factor ( M-CSF ) and interleukin 1 receptor antagonist ( IL-1ra ) significantly increased with the clinical stage of CRC, and the levels of IL-6, soluble tumor necrosis factor ( sTNF ) receptor type I ( RI ), soluble interleukin 2 receptor alpha and TNFalpha with tumor grade, while IL-6, IL-8, M-CSF, IL-1ra and sTNF RI levels significantly rose with bowel wall invasion
Zhao et al., Leukemia 2008 (Hypersensitivity, Delayed) : sorafenib also caused G ( 0 ) /G ( 1 ) phase arrest, inhibition of CD25 and CD69 expression, interleukin-2 production and LCK phosphorylation in the T cells ; all of these effects exhibited dose and time dependence
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Shirakawa et al., Mol Cell Biol 1989 : Identical results were obtained with the human natural killer-like cell line YT, which can be induced to express the interleukin-2 receptor alpha subunit in response to interleukin-1 , cyclic AMP, or phorbol 12-myristate 13-acetate