Gene interactions and pathways from curated databases and text-mining

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IL3 — LYN

Text-mined interactions from Literome

Torigoe et al., Leukemia 1992 : This finding that p53/56-LYN can be regulated by both IL-2 in B-lineage cells and IL-3 in myeloid committed cells demonstrates that the same SRC-family PTK can participate in signal transduction events mediated via two independent receptor systems
Torigoe et al., Blood 1992 (Leukemia, Myeloid, Acute...) : Because most IL-3 -- dependent cells contain p53/56-LYN, but not p56-LCK, we explored the effects of IL-3 on the activities of LYN and other SRC-like PTKs in two human leukemic cell lines, AML-193 and TALL-101, which are phenotypically myeloid, and whose in vitro growth is dependent on IL-3