◀ Back to LYN
IL3 — LYN
Text-mined interactions from Literome
Torigoe et al., Leukemia 1992
:
This finding that
p53/56-LYN can be
regulated by both IL-2 in B-lineage cells and
IL-3 in myeloid committed cells demonstrates that the same SRC-family PTK can participate in signal transduction events mediated via two independent receptor systems
Torigoe et al., Blood 1992
(Leukemia, Myeloid, Acute...) :
Because most IL-3 -- dependent cells contain p53/56-LYN, but not p56-LCK, we explored the
effects of
IL-3 on the activities of
LYN and other SRC-like PTKs in two human leukemic cell lines, AML-193 and TALL-101, which are phenotypically myeloid, and whose in vitro growth is dependent on IL-3