Gene interactions and pathways from curated databases and text-mining

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HES5 — IL8

Text-mined interactions from Literome

Yeh et al., Life Sci 2007 (Edema...) : In vitro, HES suppressed the expression of IL-8 on A549 cells and THP-1 cells, the expression of TNF-alpha, IL-1 beta, and IL-6 on THP-1 cells, the expression of ICAM-1 and VCAM-1 on A549 cells which effect cell adhesion function
Lv et al., Acta Anaesthesiol Scand 2005 : HES significantly reduced the increased hepatic levels of TNF-alpha, IL-1beta, IL-6, IL-8 and the mRNAs in the endotoxemic rats
Lv et al., J Int Med Res 2005 (Endotoxemia...) : HES significantly reduced the LPS induced increase in intestinal levels of TNF-alpha, IL-1beta, IL-6, IL-8 and their corresponding mRNAs