Gene interactions and pathways from curated databases and text-mining

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INS — RPS6KB2

Text-mined interactions from Literome

Gout et al., J Biol Chem 1998 : Similarly to p70alpha, the catalytic activity of p70beta toward ribosomal protein S6 could be rapidly activated by serum, insulin , and phorbol ester in transiently transfected cells
Wang et al., J Biol Chem 2001 (MAP Kinase Signaling System) : Here we demonstrate that in adult rat ventricular cardiomyocytes, PE and insulin each activate S6K2 , activation being 3.5- and 5-fold above basal, respectively ... Rapamycin completely blocked S6K2 activation by either PE or insulin ... However, this PKB mutant did partially block S6K2 activation by insulin , indicating PKB is required here