Gene interactions and pathways from curated databases and text-mining

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IRF1 — MAPK10

Text-mined interactions from Literome

Lee et al., Cancer Res 2005 (MAP Kinase Signaling System) : We found that IL-1beta regulated IRF-1 gene expression through stimulation of p38 mitogen activated protein kinase ( MAPK ), which mediated signal transducer and activator of transcription 1 ( Stat1 ) serine phosphorylation and Stat1 nuclear translocation to activate the IRF-1 promoter
Kanda et al., Endocrinology 2007 (MAP Kinase Signaling System...) : Inhibitors of Janus kinase ( JAK ), p38 MAPK , and MAPK/ERK kinase (MEK) suppressed prolactin- plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB, STAT1, and IRF-1 activities
Kanda et al., Eur J Immunol 2007 : Inhibitors of PI3 K, p38 MAPK , and MEK suppressed IL-18 plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB, STAT1, and IRF-1 activities
Hickey et al., J Leukoc Biol 2008 : Our findings demonstrate that CyaA modulates TLR agonist induced IL-10 and IL-12p70 production in DC by, respectively, enhancing MAPK phosphorylation and inhibiting IRF-1 and IRF-8 expression and that this is mediated by elevation of intercellular cAMP concentrations
Shen et al., Leukemia & lymphoma 2011 (Leukemia, Monocytic, Acute...) : RA induces MAPK dependent expression of IRF-1 ... Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid induced differentiation of HL-60 human myelo-monoblastic leukemia cells