Gene interactions and pathways from curated databases and text-mining

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AKT1 — ITGA6

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Bachelder et al., J Cell Biol 1999 (Colorectal Neoplasms) : p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB
Shen et al., Exp Cell Res 2006 (Breast Neoplasms) : The role of PTHrP in breast cancer growth and metastasis may thus be mediated via upregulation of integrin alpha6beta4 expression and Akt activation , with consequent inactivation of GSK-3
Bhatia et al., Mol Cancer Res 2009 (Prostatic Neoplasms) : Parathyroid hormone related protein regulates cell survival pathways via integrin alpha6beta4 mediated activation of phosphatidylinositol 3-kinase/Akt signaling