Gene interactions and pathways from curated databases and text-mining

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AKT1 — ITGB3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: AKT1 → ITGB3 (increases, ITGB3 Activity)
    Evidence: In addition, anti-beta(3) integrin antibodies attenuated the activation of both the p42/44 MAPK and protein kinase B and the increase in fibronectin levels.
  • Reactome Reaction: ITGB3 → AKT1 (reaction) Kirk et al., J Biol Chem 2000*

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *