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JAK2 — NFKB1

Text-mined interactions from Literome

Nomura et al., Toxicol Lett 1998 (Ischemic Attack, Transient) : LPS caused intranuclear translocation of NF-kappaB , and IFNgamma induced phosphorylation of Jak2 and Stat1, followed by the translocation of Stat1 into the nucleus
Carvalho et al., Oncogene 2005 (Carcinoma, Renal Cell...) : Inhibition of JAK2 , one of the receptor-proximal elements of EPO mediated signal transduction, greatly diminished the EPO mediated chemosensitization and NF-kappaB inhibition
Nefedova et al., J Immunol 2005 : Inhibition of Jak2/STAT3 signaling resulted in activation of the transcription factor NF-kappaB
Kanda et al., Endocrinology 2007 (MAP Kinase Signaling System...) : Inhibitors of Janus kinase ( JAK ) , p38 MAPK, and MAPK/ERK kinase (MEK) suppressed prolactin- plus IFN-gamma induced CXCL9, CXCL10, and CXCL11 production and NF-kappaB , STAT1, and IRF-1 activities
Hu et al., J Leukoc Biol 2007 : Similarly, basal ITAM signaling augments IFN signaling and function of receptor activator of NF-kappaB , but extensive ITAM activation inhibits Jak-STAT signaling
Huang et al., J Immunol 2007 : Requirement for both JAK mediated PI3K signaling and ACT1/TRAF6/TAK1 dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells
Jones et al., Journal of inflammation (London, England) 2007 : Here, we examine the role of protein kinase C isoforms and janus activated kinase 2 (JAK2) activation in NF-kappaB activation and LPS stimulated NO production
Pincheira et al., J Immunol 2008 : TNFR1/c-Src, but not TNFR1/Jak2 , plays an obligate role in the activation of NF-kappaB by TNF, whereas TNFR1/Jak2, but not TNFR1/c-Src, plays an obligate role in the activation of STAT3
Marrero et al., Brain Res 2009 (Inflammation) : Convergence of alpha 7 nicotinic acetylcholine receptor activated pathways for anti-apoptosis and anti-inflammation : central role for JAK2 activation of STAT3 and NF-kappaB
Qi et al., J Cell Physiol 2009 : IFN-gamma potentiates TNF-alpha induced CXCL10 production in THP-1 cells by increasing the activation of STAT1 and NF-kappaB through JAK1 and JAK2
Peña et al., J Mol Med (Berl) 2010 (Sepsis) : JAK2 inhibitor prevents the activation of the canonical p65RelA/p50NF-kappaB1 pathway but not the other NF-kappaB proteins