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IL1B — JAK3
Text-mined interactions from Literome
Finder et al., Am J Physiol Lung Cell Mol Physiol 2001
(MAP Kinase Signaling System) :
IL-1beta activated the three mitogen activated protein kinase ( extracellular signal regulated kinases 1 and 2, c-Jun NH2-terminal kinase/stress activated protein kinase, and p38 ) and the
Janus kinase ( JAK ) -signal transducer and activator of transcription pathways
Yu et al., Biochem Pharmacol 2006
(Disease Models, Animal...) :
In the present study, we investigated whether the activation of
Jak/Stat signaling
mediates IL-1beta expression in pancreatic acinar AR42J cells stimulated with cerulein in vitro as well as the rats with cerulein pancreatitis in vivo using AG490, the Jak2 inhibitor
Honsho et al., Circ Res 2009
(Endomyocardial Fibrosis...) :
Promoter analysis showed that stretch mediated
IL-1beta activates
JAK/STAT to transcriptionally regulate the IGF-1 gene