Gene interactions and pathways from curated databases and text-mining

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IL1B — JAK3

Text-mined interactions from Literome

Finder et al., Am J Physiol Lung Cell Mol Physiol 2001 (MAP Kinase Signaling System) : IL-1beta activated the three mitogen activated protein kinase ( extracellular signal regulated kinases 1 and 2, c-Jun NH2-terminal kinase/stress activated protein kinase, and p38 ) and the Janus kinase ( JAK ) -signal transducer and activator of transcription pathways
Yu et al., Biochem Pharmacol 2006 (Disease Models, Animal...) : In the present study, we investigated whether the activation of Jak/Stat signaling mediates IL-1beta expression in pancreatic acinar AR42J cells stimulated with cerulein in vitro as well as the rats with cerulein pancreatitis in vivo using AG490, the Jak2 inhibitor
Honsho et al., Circ Res 2009 (Endomyocardial Fibrosis...) : Promoter analysis showed that stretch mediated IL-1beta activates JAK/STAT to transcriptionally regulate the IGF-1 gene