Gene interactions and pathways from curated databases and text-mining

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KSR1 — MAPK7

Text-mined interactions from Literome

Channavajhala et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Although KSR is a positive regulator of the Ras/mitogen activated protein ( MAP ) kinase pathway, the role of KSR in Cot mediated MAPK activation has not been identified
Gramling et al., Cell Death Differ 2012 (Cell Transformation, Neoplastic...) : Therefore, loss of Ksr1 inhibits Ras/Mapk pathway signaling leading to increased Myc induced B-cell apoptosis, and this results in reduced B-cell transformation and lymphoma development
Joneson et al., J Biol Chem 1998 : We examined the effect of mammalian KSR expression on the activation of extracellular ligand regulated ( ERK ) mitogen activated protein ( MAP ) kinase in fibroblasts