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LRP1 — SRC

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: SRC — LRP1 (direct interaction, enzymatic study) Loukinova et al., J Biol Chem 2002*
• IRef Hprd Interaction: SRC — LRP1 (in vitro) Loukinova et al., J Biol Chem 2002*, Barnes et al., Oncogene 2003*
• IRef Hprd Interaction: SRC — LRP1 (in vivo) Loukinova et al., J Biol Chem 2002*, Barnes et al., Oncogene 2003*

Text-mined interactions from Literome

Newton et al., J Biol Chem 2005 : Using a panel of cytoplasmic domain mutants of the chimeric M-CSF/PDGFR-beta, we confirmed that the kinase domain of PDGFR-beta is absolutely required for LRP tyrosine phosphorylation but that PDGFR-beta mediated activation of phosphatidylinositol 3-kinase, RasGAP, SHP-2, phospholipase C-gamma, and Src are not necessary for LRP tyrosine phosphorylation
Shi et al., Science signaling 2009 : Binding of tissue-type plasminogen activator or alpha(2)-macroglobulin ( alpha(2)M ) to LRP1 resulted in Src family kinase (SFK) activation and SFK dependent Trk receptor transactivation in PC12 cells and neurons