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MAP3K1 — MAPK1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind_translation Interaction:
MAP3K1
—
MAPK1
(coimmunoprecipitation)
Karandikar et al., J Biol Chem 2000*
-
IRef Biogrid Interaction:
MAP3K1
—
MAPK1
(direct interaction, enzymatic study)
Gallagher et al., J Biol Chem 2004*
-
IRef Biogrid Interaction:
MAP3K1
—
MAPK1
(direct interaction, enzymatic study)
Tu et al., J Biol Chem 2003*
-
IRef Biogrid Interaction:
MAP3K1
—
MAPK1
(physical association, affinity chromatography technology)
Karandikar et al., J Biol Chem 2000*
-
IRef Hprd Interaction:
MAP3K1
—
MAPK1
(in vivo)
Karandikar et al., J Biol Chem 2000*
-
IRef Innatedb Interaction:
MAP3K1
—
MAPK1
(unknown, -)
Karandikar et al., J Biol Chem 2000*
Text-mined interactions from Literome
Uhlik et al., Biochem Cell Biol 2004
(MAP Kinase Signaling System) :
Wiring diagrams of
MAPK regulation by
MEKK1 , 2, and 3
Korchnak et al., Cell Signal 2009
:
Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase (
MAP3K ) that
activates multiple mitogen activated protein kinase (
MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
López-Pelaéz et al., Mol Biol Cell 2012
(Inflammation...) :
Cot/tpl2 is the only
MAP3K that
activates MKK1/2-Erk1/2 in Toll-like receptor activated macrophages
Xu et al., Proc Natl Acad Sci U S A 1995
:
MEKK1 phosphorylates MEK1 and MEK2 but does not
cause activation of
mitogen activated protein kinase