Gene interactions and pathways from curated databases and text-mining

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CA2 — MED21

Text-mined interactions from Literome

Waltereit et al., J Neurosci 2001 : Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen activated protein kinase/extracellular regulated kinase activation
Zawilska et al., Acta Neurobiol Exp (Wars) 1992 : It is suggested that Ca2+ may regulate NAT activity indirectly, by affecting the intracellular cyclic AMP content, which is, in turn, critical in the regulation of melatonin biosynthesis
Li et al., J Biol Chem 2005 (Polycystic Kidney Diseases) : We employed a Xenopus oocyte Ca2+ imaging system to directly investigate the role of PC2 in inositol 1,4,5-trisphosphate ( IP3 ) -dependent Ca2+ signaling
Jin et al., J Biol Chem 2007 : In contrast, under the same assay conditions, partially purified NAT from rat brain was highly Ca2+ dependent , membrane associated, and specific for the sn-1-acyl group of PC ... These results reveal that RLP-1 can function as a PE N-acyltransferase, catalytically distinguishable from the known Ca2+ dependent NAT
Wainwright et al., J Neurochem 1984 : EGTA or additional Ca2+ had no effect on pineal NAT activity
Nakamura et al., Am J Physiol 1995 : Plasmin inhibited the thrombin evoked increase in cytosolic Ca2+ and also inhibited the Ca2+ response to the tethered peptide TRAP-6 of the thrombin receptor
Kruse et al., Am J Physiol 1995 : Receptor operated effects of alpha-thrombin and of the thrombin receptor activating peptide TRAP14 on cytoplasmic Ca2+ concentration ([Ca2+]i) were examined in fura 2-loaded endothelial cells
Jenkins et al., J Cell Sci 1995 : The use of alanine substituted peptides demonstrated that the Ca2+ response was due to TRAP stimulation of a receptor other than the proteolytically activated thrombin receptor