Gene interactions and pathways from curated databases and text-mining

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JAK2 — MMP1

Text-mined interactions from Literome

Kim et al., J Lipid Res 2008 : The activation of ceramide pathway by C ( 2 ) -ceramide enhanced phosphorylation of signal transducer and activators of transcription-1 ( STAT-1 ), whereas ceramide induced MMP-1 expression was potently prevented by piceatannol ; Janus kinase ( JAK1 ) inhibtor ; and WHI-P131, a specific inhibitor of JAK3 ; but not by AG490, JAK 2 inhbitor, in human dermal fibroblasts
Korzus et al., J Biol Chem 1997 : The mitogen activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element mediated activation of matrix metalloproteinase 1 gene expression