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MMP14 — NFKB1

Text-mined interactions from Literome

Mengshol et al., Arthritis Rheum 2000 (MAP Kinase Signaling System) : In chondrosarcoma cells, MMP-1 induction depends on p38 and MEK ( an MAPK kinase of the extracellular signal regulated kinase pathway ) and does not require JNK or NF-kappaB
Han et al., J Cell Sci 2001 : TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP
Philip et al., J Biol Chem 2001 (Melanoma...) : To our knowledge, this is the first report that MMP-2 plays a direct role in OPN induced cell migration, invasion, and tumor growth and that demonstrates that OPN stimulated MMP-2 activation occurs through NF-kappaB mediated induction of MT1-MMP
Shukla et al., Neoplasia (New York, N.Y.) 2004 (Adenocarcinoma...) : The nuclear levels of NF-kappaB/p65 correlated with concurrent increase in cytosolic levels of IkappaBalpha along with NF-kappaB dependent expression of Bcl2, cyclin D1, MMP-9 , and VEGF
Dai et al., Ann Rheum Dis 2005 (Arthritis...) : In chondrocytes responding to IL18, IL18 ( 1-100 ng/ml ) slightly increased the production of MMP-1, MMP-3 , and MMP-13, which was blocked by NF-kappaB inhibitor and p38 mitogen activated protein kinase inhibitor
Yoshida et al., Respirology 2006 (Pulmonary Emphysema) : A specific inhibitor of NF-kappaB reduced MMP production by alveolar macrophages from SP-D-/- mice
Fan et al., Rheumatol Int 2006 : Role of mitogen activated protein kinases and NFkappaB on IL-1beta induced effects on collagen type II, MMP-1 and 13 mRNA expression in normal articular human chondrocytes
Park et al., Carcinogenesis 2007 (Fibrosarcoma...) : MT1-MMP expression is regulated by NF-kappaB
Bachmeier et al., Cell Physiol Biochem 2007 (Breast Neoplasms...) : 68 % of Curcumin treated but only 17 % of untreated animals showed no or very few lung metastases, most likely as a consequence of down-regulation of NFkappa B/AP-1 dependent MMP expression and direct apoptotic effects on circulating tumor cells but not on established metastases
Miller et al., Invest Ophthalmol Vis Sci 2007 : Lactate treatment resulted in dose- and time dependent effects on human TM cell viability, translocation of NF-kappaB , and activation of MT1-MMP
Bogatkevich et al., Arthritis Rheum 2007 (MAP Kinase Signaling System...) : Inhibition of MMP activity by MMP inhibitor GM1489 and inhibition of MMP-1 expression by siRNA did not prevent HGF induced ERK-1/2 phosphorylation and NF-kappaB activity, but significantly restored HGF inhibited collagen and CTGF accumulation
Wu et al., Cancer Lett 2009 (Carcinoma, Hepatocellular...) : Inhibition of NF-kappaB activity significantly reduced proliferation and invasion of Hep3B cells as well as down-regulated the expression of invasion related molecules including matrix metalloproteinase (MMP)-2, MMP-9, membrane type-1 MMP (MT1-MMP) , urokinase plasminogen activator (uPA) and vascular endothelial growth factor ( VEGF )
Castier et al., Antioxid Redox Signal 2009 : Hence, induction of NF-kappaB by shear stress contributes to MMP induction and allows long-term flow induced vascular enlargement
Moon et al., Int Immunopharmacol 2010 (Arthritis, Experimental...) : Additionally, by altering nuclear factor (NF)-kappaB transcription activity in FLSs, curcumin inhibited PGE ( 2 ) production, COX-2 expression, and MMP secretion
Fritz et al., Mol Cancer Res 2010 (Breast Neoplasms...) : Ectopic expression of CNK1 elevates MT1-MMP promoter activity in a NF-kappaB dependent manner
Martinez-Orozco et al., Eur J Cell Biol 2010 (Neoplasm Invasiveness) : We demonstrate here that AA promotes an increase in vimentin and N-cadherin expression, MMP-9 secretion, a decrease in E-cadherin junctional levels, and the activation of FAK, Src and NF-kappaB in MCF10A cells