Gene interactions and pathways from curated databases and text-mining

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MS — TNF

Text-mined interactions from Literome

Bitsch et al., Glia 2000 (Demyelinating Diseases...) : The precise role of tumour necrosis factor alpha (TNFalpha) in multiple sclerosis (MS) is still controversial
Zai-Xing et al., J Clin Lab Anal 2008 (Arthritis, Rheumatoid...) : It has recently been reported that tumor necrosis factor (TNF) related apoptosis inducing ligand ( TRAIL ) plays various roles in such autoimmune diseases as diabetes, multiple sclerosis (MS) , and systemic lupus erythematosus ( SLE )
Zipp et al., Ann Neurol 1995 (Disease Susceptibility...) : Genetic control of multiple sclerosis : increased production of lymphotoxin and tumor necrosis factor-alpha by HLA-DR2+ T cells
Claudio et al., Lab Invest 1994 : These results demonstrate that proinflammatory effects of IL-1 beta and TNF-alpha in the BRB initiate many of the changes associated with inflammation of the CNS vasculature, such as those induced during experimental autoimmune encephalitis and multiple sclerosis
Rieckmann et al., J Neuroimmunol 1996 (Autoimmune Diseases...) : Increasing doses of PTX significantly reduced TNF-alpha and IL-12 mRNA expression of blood mononuclear cells, but increased IL-4 and IL-10 expression in eight patients with relapsing remitting multiple sclerosis
Salmaggi et al., J Neurol 1997 (Multiple Sclerosis) : The decrease in TNF-alpha levels and the increase in `` suppressor-inducer '' lymphocytes could reduce chronic inflammation in multiple sclerosis , and paralleled an overall favourable clinical response to azathioprine treatment in our patients