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EPHB2 — MSH4

Text-mined interactions from Literome

Chai et al., Peptides 2006 (MAP Kinase Signaling System) : NDP-MSH stimulated ERK1/2 phosphorylation in a dose dependent manner
Chai et al., Regul Pept 2007 : NDP-MSH induced ERK1/2 phosphorylation was sensitive to pertussis toxin and the PI3K inhibitor, wortmannin ... Rp-cAMPS, BAPTA-AM and Myr-PKC did not inhibit the NDP-MSH induced ERK1/2 phosphorylation
Rodrigues et al., Mol Cell Endocrinol 2009 (MAP Kinase Signaling System) : Moreover, in cells stably expressing MC5R-GFP, alpha-MSH promoted ERK1/2 phosphorylation in a dose dependent manner ( EC50=7.3 nM ) with the maximal effect occurring after 5 min of agonist incubation ... However, alpha-MSH induced ERK1/2 activation is abolished by the phosphatidylinositol 3-kinase (PI3K) inhibitors wortmannin and LY294002