Gene interactions and pathways from curated databases and text-mining

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NCF1 — NFKB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Sadikot et al., J Immunol 2004 (Pneumonia, Bacterial...) : p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia
Gauss et al., J Leukoc Biol 2007 : Pharmacological inhibitors of NF-kappaB activation blocked TNF-alpha induced up-regulation of NCF1 , NCF2, and CYBB message, which correlated with a reduction in expression of the corresponding oxidase proteins and decreased O2*- production
Luengo-Blanco et al., Blood 2008 (Ectodermal Dysplasia...) : This work investigated the functional role of nuclear factor-kappaB (NF-kappaB) in respiratory burst activity and in expression of the human phagocyte nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase genes CYBB, CYBA, NCF1 , and NCF2 ... This work investigated the functional role of nuclear factor-kappaB (NF-kappaB) in respiratory burst activity and in expression of the human phagocyte nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase genes CYBB, CYBA, NCF1 , and NCF2 ... These studies show that NF-kappaB is necessary for CYBB and NCF1 gene expression and activation of the phagocyte NADPH oxidase in this model system