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NEUROD1 — NR4A2
Text-mined interactions from Literome
Sakurada et al., Development 1999
:
Overexpression of
Nurr1 does not affect proliferation or
stimulate neuronal differentiation and has no influence on the expression of other dopaminergic markers
Satoh et al., Neuropathology 2002
:
The constitutive and inducible expression of
Nurr1 , a key
regulator of dopaminergic
neuronal differentiation , in human neural and non-neural cell lines
Kim et al., Biochem Biophys Res Commun 2003
:
Nurr1 overexpression
induces neuronal differentiation and confers competence to respond to extrinsic signals such as Shh and FGF-8 that induce dopaminergic fate in a mouse neural stem cell line
Park et al., J Cell Sci 2006
:
In this study, we demonstrate that neurogenic basic helix-loop-helix ( bHLH ) factors Mash1, neurogenins ( Ngns ) and NeuroD play contrasting roles in
Nurr1 induced DA
neuronal differentiation
Sousa et al., Stem Cells 2007
:
These findings are accompanied by a dynamic pattern of gene regulation that is consistent with a
role for
Nurr1 in promoting both the acquisition of brain-region-specific identity ( Engrailed-1 ) and
neuronal differentiation ( tubulin beta III )
Bae et al., FEBS Lett 2009
:
We defined diffusible factors and downstream neurogenic TFs responsible for the
Nurr1 mediated
neuronal differentiation