Gene interactions and pathways from curated databases and text-mining

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CA2 — P2RY1

Text-mined interactions from Literome

Fam et al., J Neurosci 2003 (Astrocytoma...) : We report here that P2Y1R mediated and P2Y2R mediated Ca 2+ responses differentially show two forms of activity dependent negative feedback
Guerra et al., Pflugers Arch 2004 : These data suggest that the X laevis P2Y1 receptor in A6 cells can increase both cAMP/PKA and Ca2+/PKC intracellular levels and that the PKC pathway is involved in CFTR activation via potentiation of the PKA pathway
Vial et al., Biochem Biophys Res Commun 2006 : We show that disruption of cholesterol-rich membrane lipid rafts reduces P2X1 receptor mediated calcium increases by approximately 80 %, while P2Y1 receptor dependent Ca2+ release is unaffected
Rubini et al., J Cell Physiol 2006 (Calcium Signaling) : Regulation of intracellular Ca2+ by P2Y1 receptors may depend on the developmental stage of cultured rat striatal neurons
Domercq et al., J Biol Chem 2006 : Accordingly, astrocytes from TNFalpha-deficient ( TNF ( -/- ) ) or TNF type 1 receptor-deficient ( TNFR1 ( -/- ) ) mice display altered P2Y1R dependent Ca2+ signaling and deficient glutamate release ... P2Y1R stimulation induces Ca2+ -dependent glutamate release also from acute hippocampal slices
Yamazaki et al., J Pharmacol Sci 2007 : ATP-receptor ( P2Y ) stimulation induced sustained Ca2+-entry , which was essential for the enhanced cell-proliferation in t-BBEC117, an immortalized cell-line derived from bovine brain endothelial cells
Wu et al., J Neurosci 2007 : Purinergic receptor stimulated IP3 mediated Ca2+ release enhances neuroprotection by increasing astrocyte mitochondrial metabolism during aging
Rubini et al., Neurochem Int 2008 : Regulation of intracellular Ca2+ by P2Y1 receptors may depend on the developmental stage of cultured rat striatal neurons
Tudurí et al., Am J Physiol Endocrinol Metab 2008 (Calcium Signaling) : Using pharmacological agonists, we found that only P2Y1 and A2A were likely involved in the inhibitory effect on Ca2+ signaling
Lyubchenko et al., Am J Physiol Cell Physiol 2011 (Calcium Signaling) : P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells
Kitazono et al., Biochem Biophys Res Commun 1988 : The results indicate that ATP activates the Na+/H+ exchanger in cultured bovine aortic endothelial cells and the activation is mediated by the P2-purinergic receptor and is dependent on the extracellular Ca2+
Doan et al., Biochem J 1994 : The effect of the biological oxidant H2O2 on purinergic-receptor stimulated Ca2+ signalling was determined in canine venous endothelial cells