Gene interactions and pathways from curated databases and text-mining

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CA2 — PDCD1

Text-mined interactions from Literome

Trubiani et al., Int J Immunopathol Pharmacol 2003 : Our results are consistent with the hypothesis that programmed cell death can be induced by up regulation of the intracellular Ca2+ associated with an increase of cell membrane fluidity
Zacharchuk et al., J Immunol 1991 : Moreover, thymocytes of all ages were equally susceptible to corticosteroid- and Ca2+ ionophore induced programmed cell death
Zhao et al., Mol Med Report 2013 : The mitochondrial calcium uniporter (MCU) maintains intracellular Ca2+ homeostasis by transporting Ca2+ from the cell cytosol into the mitochondrial matrix and is important for shaping Ca2+ signals and the activation of programmed cell death
Lam et al., Mol Endocrinol 1993 (Lymphoma) : There is growing evidence for the involvement of Ca2+ in the programmed cell death ( apoptosis ) of lymphocytes, but the nature of glucocorticoid induced Ca2+ fluxes and their role in the cell death pathway are poorly understood