Gene interactions and pathways from curated databases and text-mining

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NFKB1 — PDCD1

Text-mined interactions from Literome

Tietze et al., Cancer Gene Ther 2000 (Carcinoma, Hepatocellular...) : Several reports have indicated that NFkappaB may also inhibit the programmed cell death induced by cytokines, ionizing radiation, or cytotoxic drugs in some cancer cell lines
Ivanov et al., Oncogene 2001 (Melanoma) : Our finding identifies p38, TNFalpha and NF-kappaB among key players that efficiently sensitizes melanoma cells to UV-, ribotoxic ( anisomycin ) and radiomimetic chemicals induced programmed cell death in response to aberrant TRAF2 signaling
Maalouf et al., Mol Carcinog 2002 : Exposure of human skin to UVB radiation leads to the depletion of cutaneous antioxidants, the activation of nuclear factor kappa B (NF-kappaB) , and programmed cell death ( apoptosis )
Greten et al., Gastroenterology 2002 (Carcinoma, Ductal, Breast...) : Functional analysis shows that blocking of both Stat3 and NF-kappaB together induces programmed cell death in murine pancreatic tumor cells
Häcker et al., Cancer Cell 2002 (Cell Transformation, Neoplastic...) : Is NF-kappaB2/p100 a direct activator of programmed cell death ?
Nitta et al., Cell Signal 2003 (Cell Transformation, Viral) : Here, we demonstrate that expression of latent membrane protein 1 (LMP1), an Epstein-Barr virus ( EBV ) -encoded membrane protein, triggers programmed cell death in an NF-kappaB dependent manner
Wright et al., Am J Respir Med 2003 (Lung Diseases) : Results of studies in in vitro and in vivo models of inflammation and malignancy have also suggested central roles for NF-kappaB in programmed cell death , or apoptosis
Nitta et al., Cell Signal 2004 (Nasopharyngeal Neoplasms) : Our recent report demonstrated that expression of LMP1 induced programmed cell death in an NF-kappaB dependent manner
Zeng et al., Am J Physiol Gastrointest Liver Physiol 2006 (Inflammation) : However, when NF-kappaB mediated or phosphatidylinositol 3-kinase/Akt proinflammatory signaling was blocked, flagellin could induce programmed cell death
Dutta et al., Oncogene 2006 (Cell Transformation, Viral...) : Current insights into the regulation of programmed cell death by NF-kappaB
Cruz et al., Infect Immun 2008 (Inflammation...) : Our combined results demonstrate that B. burgdorferi confined to phagolysosomes is a potent inducer of cytosolic signals that result in ( i ) production of NF-kappaB dependent cytokines, ( ii ) assembly of the inflammasome and activation of caspase-1, and ( iii ) induction of programmed cell death
Fan et al., Adv Exp Med Biol 2008 (Neoplasms) : Regulation of programmed cell death by NF-kappaB and its role in tumorigenesis and therapy
Momeny et al., Med Oncol 2010 : Microculture tetrazolium test, bromodeoxyuridine ( BrdU ) cell proliferation assay, caspase 3 activity assay, cell based nuclear factor kappa B (NF-kappaB) phosphorylation measurement by ELISA and real-time RT-PCR were employed to appraise the effects of ATO on metabolic activity, DNA synthesis, induction of programmed cell death and NF-kappaB activation
Jung et al., Radiat Res 1998 (Ataxia Telangiectasia) : These data suggest that regulation of NF-kappaB may play an important role in programmed cell death induced by DNA damage in AT cells