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NFKB1 — PIAS4
Text-mined interactions from Literome
Zhang et al., FEBS Lett 2004
:
PIASy represses TRIF induced ISRE and
NF-kappaB activation but not apoptosis ... In reporter gene assays,
PIASy dramatically
inhibits TRIF induced
NF-kappaB , ISRE and IFN-beta activation but not TRIF induced apoptosis
Shuai et al., Cell Res 2006
:
This article is to review the
role of
PIAS proteins in the regulation of STAT and
NF-kB signaling pathways
Albor et al., J Biol Chem 2006
(Muscular Dystrophies, Limb-Girdle) :
Conversely,
Piasy inhibited
NFkappaB activity under the same conditions and sensitized keratinocytes to apoptosis induced by TNFalpha and UVB
Mabb et al., Nat Cell Biol 2006
:
PIASy mediates NEMO sumoylation and
NF-kappaB activation in response to genotoxic stress
Albor et al., Mol Carcinog 2007
(Carcinoma, Squamous Cell...) :
Piasy inhibits
NF-kappaB activity, and promotes keratinocyte apoptosis in response to UV and TNF-alpha