Gene interactions and pathways from curated databases and text-mining

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PIK3CG — RELA

Text-mined interactions from Literome

Chandrasekar et al., J Biol Chem 2004 (Arteriosclerosis...) : However, treatment with pertussis toxin ( G ( i ) inhibitor ), wortmannin or LY294002 ( phosphatidylinositol 3-kinase ( PI3K inhibitors ) ), or Akt inhibitor or overexpression of dominant negative ( dn ) PI3K gamma , dnPDK-1, kinase-dead ( kd ) Akt, kdIKK-beta, dnIKK-gamma, dnI kappa B-alpha, or dnI kappa B-beta significantly attenuated CXCL16 induced NF-kappa B activation
Frey et al., J Biol Chem 2006 : Additionally, the TNFalpha activated NF-kappaB binding to the ICAM-1 promoter, ICAM-1 protein expression, and PMN adhesion to ECs required functional PI3Kgamma