Gene interactions and pathways from curated databases and text-mining

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JUN — PIN1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Barone et al., J Neurochem 2008 : Downregulating Pin1 prior to NGF withdrawal suppressed the accumulation of phosphorylated c-Jun , inhibited the release of cytochrome c, and significantly delayed cell death
Lee et al., Carcinogenesis 2009 (Carcinoma, Hepatocellular...) : Hence, Pin1 affected activator protein-1 activity through p70S6K-ERK1/2 signaling in SK-HEP-1 cells
Rouzer et al., Cancer prevention research (Philadelphia, Pa.) 2011 (Neoplasms) : They showed that Pin1 expression is required for EGCG effects on cell growth, c-Jun activation, and transcription regulation mediated by NF-?B and activator protein-1