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JUN — PIN1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Barone et al., J Neurochem 2008
:
Downregulating
Pin1 prior to NGF withdrawal
suppressed the accumulation of phosphorylated
c-Jun , inhibited the release of cytochrome c, and significantly delayed cell death
Lee et al., Carcinogenesis 2009
(Carcinoma, Hepatocellular...) :
Hence,
Pin1 affected
activator protein-1 activity through p70S6K-ERK1/2 signaling in SK-HEP-1 cells
Rouzer et al., Cancer prevention research (Philadelphia, Pa.) 2011
(Neoplasms) :
They showed that
Pin1 expression is
required for EGCG effects on cell growth,
c-Jun activation, and transcription regulation mediated by NF-?B and activator protein-1