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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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PKD3 — RELA

Text-mined interactions from Literome

Storz et al., EMBO J 2003 : PKD activates NF-kappaB through the IKK complex and more specifically, IKKbeta, leading to I(kappa)B(alpha) degradation
Storz et al., Mol Cell Biol 2004 : We also show that other PKCs, including PKCepsilon and PKCzeta, do not participate in PKD activation or NF-kappaB induction
Storz et al., Mol Pharmacol 2004 : Resveratrol, a potent antioxidant, blocks both PKD activation and NF-kappaB induction
Arnold et al., Mol Cell Biol 2005 : Upon T-cell receptor stimulation, PKD robustly augments HPK1 kinase activity in Jurkat T cells and enhances HPK1-driven SAPK/JNK and NF-kappaB activation ; conversely, antisense down-regulation of PKD results in reduced HPK1 activity