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JUN — PML
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
PML
—
JUN
(colocalization, imaging technique)
Yasuda et al., Genes Cells 1999*
-
IRef Biogrid Interaction:
PML
—
JUN
(physical association, affinity chromatography technology)
Salomoni et al., Blood 2005*
-
IRef Biogrid Interaction:
PML
—
JUN
(physical association, affinity chromatography technology)
Seo et al., Mol Cell 2006*
-
IRef Biogrid Interaction:
PML
—
JUN
(direct interaction, pull down)
Seo et al., Mol Cell 2006*
-
IRef Biogrid Interaction:
PML
—
JUN
(direct interaction, pull down)
Vallian et al., Oncogene 1998*
-
IRef Hprd Interaction:
Complex of 17 proteins
(in vivo)
Vallian et al., Oncogene 1998*
Text-mined interactions from Literome
Salomoni et al., Blood 2005
:
We demonstrate that c-Jun is required for UV-induced apoptosis and that
PML is
essential for both
c-Jun transcriptional activation and DNA binding upon UV radiation
Cheng et al., J Biol Chem 2005
:
However, the ability of SuPr-1 to enhance
c-Jun transcription is
dependent on
promyelocytic leukemia but is independent of the desumoylation activity of SuPr-1
Santiago et al., Cell cycle (Georgetown, Tex.) 2009
:
PML also
activates c-Jun , which requires all three sumoylation sites
Vallian et al., Oncogene 1998
:
There is significant sequence homology between the dimerization domain of PML and the Fos family of proteins, which imply that
PML may be
involved in
AP-1 activity