Gene interactions and pathways from curated databases and text-mining

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EPHB2 — POU5F1

Text-mined interactions from Literome

Luo et al., Clin Exp Pharmacol Physiol 2012 (MAP Kinase Signaling System) : 4. The data indicate that HG facilitates cell cycle arrest of rat MAPC through TGF-ß1 induced activation of ERK1/2 signalling and p21 expression, and that Oct4 expression in MAPC is independent of the cell cycle and/or TGF-ß1 or ERK1/2 signalling in HG medium
Spelat et al., J Biol Chem 2012 : To investigate the possibility that ERK1/2 activation can enhance OCT4A degradation, we analyzed endogenous ubiquitination in cells transfected with FLAG-OCT4A alone or with constitutively active MEK1 ( MEK1 ( CA ) ), and we observed that the extent of OCT4 ubiquitination was clearly increased when MEK1 ( CA ) was coexpressed and that this increase was more evident after MG132 treatment