◀ Back to RELA

PRKCD — RELA

Pathways - manually collected, often from reviews:

• NCI Pathway Database LPA receptor mediated events: PKC delta (PRKCD) → NF kappa B1 p50/RelA/I kappa B alpha complex (NFKB1-NFKBIA-RELA) (modification, activates)
  Cummings et al., J Biol Chem 2004
  Evidence: mutant phenotype, assay

Text-mined interactions from Literome

Rahman et al., Circ Res 2002 : Expression of the kinase-defective protein kinase C (PKC)-delta mutant inhibited NF-kappaB activation induced by the constitutively active Galpha ( q ) mutant, but had no effect on NF-kappaB activity induced by Gbeta ( 1 ) gamma ( 2 )
Miskolci et al., Arch Biochem Biophys 2003 : Furthermore, inhibitors of protein kinase C-delta (PKCdelta) and IkappaB kinase (IKK) inhibit the OA-induced activation of NFkappaB
Cummings et al., J Biol Chem 2004 (Inflammation) : Here, we report that protein kinase Cdelta (PKCdelta) mediates LPA induced NF-kappaB transcription and interleukin-8 (IL-8) secretion in HBEpCs
Zhao et al., J Biol Chem 2006 : We have demonstrated earlier that lysophosphatidic acid (LPA) induced interleukin-8 (IL-8) secretion is regulated by protein kinase Cdelta (PKCdelta) dependent NF-kappaB activation in human bronchial epithelial cells ( HBEpCs )