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PSMB9 — TNF
Text-mined interactions from Literome
Marqués et al., J Immunol 2004
:
In murine bone marrow derived macrophages, LPS and
TNF-alpha induced Tap1 and
up-regulated Lmp2 , which is constitutively expressed at low levels ... In macrophages from STAT-1 knockout mice, neither LPS nor
TNF-alpha induced the expression of Tap1 or
Lmp2 ... These results show that LPS and
TNF-alpha regulate the induction of Tap1 and
Lmp2 through STAT1, but use distinct areas of the promoter
Tan et al., J Burn Care Res 2006
(Burns) :
Effects of
tumor necrosis factor-alpha on the
26S proteasome and 19S regulator in skeletal muscle of severely scalded mice ... The results showed that
TNF-alpha and burn can markedly
increased the activities and contents of
26S proteasome and 19S regulator in mice skeletal muscle
Bardag-Gorce et al., Exp Mol Pathol 2010
(Disease Models, Animal...) :
SAMe prevented the increase in the TNFalpha and IFNgamma receptors, supporting the idea that
TNFalpha and IFNgamma were
responsible for the up regulation of
LMP2 , LPM7, and FAT10
Wright et al., J Exp Med 1995
:
An adjacent GC box was required for basal expression of both genes as well as augmenting the
TNF-alpha induction of the distal
LMP2 gene