Gene interactions and pathways from curated databases and text-mining

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IL8 — PTPN22

Text-mined interactions from Literome

Challacombe et al., J Immunol 2006 (Necrosis...) : Both in vitro and in mice, PEP005 induced MIP-2/IL-8 , TNF-alpha, and IL-1beta, all mediators of neutrophil recruitment and activation
Spalinger et al., PloS one 2013 : Loss of PTPN22 enhanced mRNA levels and secretion of interleukin (IL)-6, IL-8 and TNF in THP-1 cells and PTPN22 knockout BMDC