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PTPRC — SRC

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: SRC → PTPRC (increases, PTPRC Activity, SRC Activity) Kulas et al., J Biol Chem 1996*
  Evidence: These observations indicate that CD45 can function as a negative modulator of growth factor receptor tyrosine kinases in addition to its well-established role as an activator of src family tyrosine kinases.

Text-mined interactions from Literome

Kung et al., Eur J Immunol 1999 : We conclude that CD45AP is not essential for the regulation of Src-family kinase activity by CD45
Yu et al., Clin Exp Immunol 2002 : However, only anti-CD45RO suppressed Src family protein tyrosine kinase p56lck expression in the cells
Roach et al., Curr Biol 1997 : CD45 regulates Src family member kinase activity associated with macrophage integrin mediated adhesion