Gene interactions and pathways from curated databases and text-mining

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AKT1 — PXN

Text-mined interactions from Literome

Lee et al., Oncol Rep 2010 (Colonic Neoplasms) : Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1 mediated paxillin and AKT activation ... These results suggest that integrin beta1 sialylation may play a critical role in promoting adhesion of cancer cells by integrin beta1 mediated paxillin and AKT activation
Metalli et al., Am J Pathol 2010 (Cell Transformation, Neoplastic...) : The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen activated protein kinase dependent activation of paxillin