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CA2 — RAC2

Text-mined interactions from Literome

Arrieumerlou et al., J Immunol 2000 (Calcium Signaling) : The major inhibitory effect of Rac mutants on Ca2+ signaling is exerted on the activity of phospholipase C-gamma and, before that, on the phosphorylation of ZAP-70 and of the linker molecule for activation of T cells, LAT
Mehta et al., J Biol Chem 2005 : We investigated the role of intracellular Ca2+ in signaling Rac activation and the enhancement of endothelial barrier function ... Thus, our results demonstrate that S1P promotes endothelial junctional integrity by activating the release of endoplasmic reticulum-Ca2+ , which induces Rac activation and promotes AJ annealing
Grunicke et al., Crit Rev Eukaryot Gene Expr 2009 (Calcium Signaling) : Likewise, Ras as well as Rac control regulatory mechanisms, resulting in increased or diminished levels of cytosolic-free Ca2+ ... The biochemical mechanisms underlying these effects are discussed, with special reference to regulation of Ca2+ signaling by Ras and Rac