◀ Back to NFKB1

NFKB1 — RBBP7

Text-mined interactions from Literome

Rahman et al., Biochem Pharmacol 2002 (Pneumonia) : Pharmacological inhibition of HDAC leads to the increased HAT activity, AP-1 and NF-kappaB activation, and IL-8 release by H2O2 or TNF-alpha treatments
Mayo et al., J Biol Chem 2003 (Carcinoma, Non-Small-Cell Lung...) : Because the anti-apoptotic transcription factor NF-kappa B has been shown to be under the control of HDAC mediated repression, we analyzed whether HDAC inhibitors activated NF-kappa B in NSCLC cells ... HDAC inhibitors effectively stimulated endogenous NF-kappa B-dependent gene expression by up-regulating IL-8, Bcl-XL, and MMP-9 transcripts
Singh et al., Oncogene 2005 (Breast Neoplasms) : HDAC inhibitors synergized with TRAIL by inducing DRs DR4/TRAIL-R1 and DR5/TRAIL-R2 through NFkappaB activation and some of the proapoptotic members of the Bcl-2 family, and engaging the mitochondrial pathway
Place et al., Biochem Pharmacol 2005 : HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity : down-regulation of proteasome subunit expression stabilizes I kappa B alpha
Shetty et al., Mol Cell Biol 2005 (Breast Neoplasms) : Indeed, HDAC inhibitors activate NF-kappaB and p53 and upregulate DR5 expression
Graham et al., Cell cycle (Georgetown, Tex.) 2005 : In addition, HDAC inhibitors induce NFkappaB binding to the DR5 gene and DR5 expression, contributing to HDAC inhibitor induced apoptosis
Kammanadiminti et al., J Biol Chem 2006 (Colitis) : Overexpression of wild type Hsp27 amplified the effects of SAP, whereas a phosphorylation-deficient mutant of Hsp27 abrogated SAP induced NF-kappaB inhibition
Kim et al., Biochem Biophys Res Commun 2006 : Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kappaB activation by the HDAC inhibitor apicidin
Andresen et al., J Immunol 2007 : NF-kappaB activity can be induced by HDAC treatment
Chavey et al., Mol Pharmacol 2008 (Breast Neoplasms) : In summary, our results demonstrate that NF-kappaB pathway repression by HDAC is responsible for the low expression of IL-8 in ERalpha positive breast cancer cells
Farhana et al., Mol Cancer Ther 2009 : We examined the effect of loss of SHP and Sin3A expression in a number of cell types on 3-Cl-AHPC mediated growth inhibition and apoptosis induction, 3-Cl-AHPC mediated nuclear factor-kappaB (NF-kappaB) activation, and 3-Cl-AHPC mediated increase in c-Fos and c-Jun expression
Zhang et al., Am J Physiol Heart Circ Physiol 2010 (Disease Models, Animal...) : Luciferase assay demonstrated an activation of NF-kappaB by HDAC inhibition