Gene interactions and pathways from curated databases and text-mining

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IL6 — REL

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Jeon et al., Toxicol Lett 1999 : Treatment of AAF to RAW 264.7 cells induced a dose related inhibition of NF-kappa B/Rel in chloramphenicol acetyltransferase activity, while either AP-1 or NF-IL6 activation was not affected by AAF
Jeon et al., Immunopharmacology 2000 : Treatment of DEX to RAW 264.7 cells induced a dose related inhibition of NF-kappaB/Rel and AP-1 in chloramphenicol acetyltransferase activity, while neither NF-IL6 nor CREB/ATF activation was affected by DEX
Grumont et al., J Exp Med 2001 : c-Rel regulates interleukin 12 p70 expression in CD8 ( + ) dendritic cells by specifically inducing p35 gene transcription
Temmerman et al., Blood 2006 (Ectodermal Dysplasia...) : As a consequence, CD40 stimulated EDI DCs failed to synthesize the c-Rel dependent cytokine interleukin-12 , had impaired up-regulation of costimulatory molecules, and failed to support allogeneic lymphocyte proliferation in vitro
Jeon et al., Biochem Mol Biol Int 1998 : Treatment of DEX to RAW 264.7 cells induced a dose related inhibition of NF-kappa B/Rel in chloramphenicol acetyltransferase activity, while NF-IL6 or Oct activation was not affected by DEX