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AKT3 — RHOA

Text-mined interactions from Literome

Viswambharan et al., Circ Res 2004 : In conclusion, rHDL inhibits thrombin induced human endothelial TF expression through inhibition of RhoA and activation of PI3K but not Akt/eNOS
Reuveny et al., FEBS Lett 2004 : Here, we show that inhibition of RhoA prevents the phosphorylation of Akt , but does not affect the phosphorylation of ERK
Ueda et al., Exp Cell Res 2004 : Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells
Gakidis et al., J Cell Biol 2004 : beta2 induced activation of Cdc42, Rac1, and RhoA is defective in Vav1/3ko neutrophils, and phosphorylation of Pyk2, paxillin, and Akt is also significantly reduced
Liao et al., J Investig Med 2004 (Cardiomegaly...) : Furthermore, inhibition of RhoA by statins leads to the activation of protein kinase B/Akt and up-regulation of endothelial nitric oxide synthase in the endothelium and the heart
Mital et al., Semin Vasc Med 2004 (Cardiomegaly) : Furthermore, inhibition of RhoA by statins leads to the activation of protein kinase B/Akt and upregulation of Type 3 nitric oxide synthase in the endothelium and the heart
Khwaja et al., Kidney Int 2006 : GGTI 298 increased cytosolic expression of RhoA, prevented RhoA activation, and inhibited the activation of Erk1/2 and the survival protein Akt
Guilluy et al., J Biol Chem 2007 (Anoxia...) : In contrast, inhibition of 5-HT mediated RhoA degradation by MG132 prevented 5-HT induced Akt activation
Charette et al., Oncogene 2007 : Increased migration in E7-expressing HFKs correlated with an Akt regulated downregulation of RhoA activity through p27 binding under conditions where a p27 nuclear import signal is given ( that is, DNA damage )
Del Re et al., J Biol Chem 2008 : Inhibition of RhoA mediated Akt activation at any of these steps, including inhibition of FAK, prevents RhoA from protecting cardiomyocytes against apoptotic insult
Nandy et al., J Cell Mol Med 2010 (Diabetes Mellitus, Type 2) : Paradoxically, inhibition of GSK-3beta phosphorylation also augmented monocyte migration in THP-1, ND and diabetic monocytes through phosphorylation of AKT and activation of Rho-A that was independent of GSK
Liu et al., Cell Signal 2013 (Stomach Neoplasms) : PI3K/Akt dependent phosphorylation of GSK3ß and activation of RhoA regulate Wnt5a induced gastric cancer cell migration
Wang et al., Ann Neurol 2013 (Brain Ischemia...) : Furthermore, rADAMTS13 downregulated tPA induced phosphorylation of Akt and activation of RhoA
Zhang et al., Circ Res 2013 (Hyperplasia...) : Inhibition or deletion of EP3a/ß, a Gai protein coupled receptor, activated the cAMP/protein kinase A pathway and decreased activation of RhoA in VSMCs. PGE2 could stimulate phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase3ß signaling in VSMCs through Gß? subunits on EP3a/ß activation