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IL6 — RLN3

Text-mined interactions from Literome

Dschietzig et al., Regul Pept 2009 : In contrast, relaxin and modified relaxin inhibited endotoxin stimulated secretion of TNF-alpha and IL-6 by human macrophages, an effect sensitive to the glucocorticoid receptor antagonists RU-486 and D-06
Horton et al., Placenta 2012 : When all cell types were treated with IL1B and RLN, RLN augmented secretion of IL6 and IL8 from CyT and DF, but not DSC ... Similarly, RLN augmented LPS induced IL6 secretion from CyT and DF ... Despite the structural similarity between TLR4 and RXFP1, blocking TLR4 in CyT had no effect on RLN induced IL6 secretion, suggesting specific activation of RXFP1