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CA2 — RNPEP

Text-mined interactions from Literome

Missiaen et al., Cell Calcium 2001 : 2APB inhibited the IP3 -induced Ca2+ release, with a half maximal inhibition at 36 microM 2APB, without affecting [ 3H]IP3 binding to the receptor
Kukkonen et al., Neuroreport 2001 (Calcium Signaling) : 2-APB did not block inositol-1,4,5- trisphosphate dependent Ca2+ release in these cells
Hirst et al., J Physiol 2001 : Slow waves were abolished by 2APB , an inhibitor of IP ( 3 ) -induced Ca2+ release
Bilmen et al., Eur J Biochem 2002 : 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+ binding sites
Kito et al., J Physiol 2002 (Calcium Signaling) : Thapsigargin ( an inhibitor of calcium-ATPase at internal stores ), 2-aminoethoxydiphenyl borate ( 2-APB , an inhibitor of inositol 1,4,5-trisphosphate ( IP3 ) -receptor mediated Ca2+ release ), and carbonyl cyanide m-chlorophenyl-hydrazone ( a mitochondrial protonophore ) reduced the amplitude of slow potentials, with no significant alteration of the refractory period
Gregory et al., Cell Calcium 2003 : In the presence of 2-APB ( to block SOCs ), maitotoxin induced a substantial increase in [Ca2+ ] ( cyt ), but only a modest and slower increase in [Ca2+ ] ( er )
Kito et al., J Smooth Muscle Res 2003 (Stomach Diseases) : 2-APB , an inhibitor of the IP3-receptor mediated Ca2+ release from internal stores, abolishes pacemaker potentials, suggesting that the release of Ca2+ from internal IP3-sensitive Ca2+ stores is required for generation of pacemaker potentials
Wuest et al., Eur J Pharmacol 2007 : Carbachol induced release of intracellular Ca2+ in Chinese hamster ovary cells expressing muscarinic hM3 receptors was completely prevented by 100 microM 2-APB
Sekaran et al., J Neurosci 2007 : Here, we show that 2-APB is an extremely potent in vitro inhibitor of the photosensitive RGCs and that its effect is independent of store dependent Ca2+ release