Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Mahapatra et al., J Biol Chem 2003 : Secretin also augmented ( approximately 4-fold ) phosphorylation of ERK1/2
Harikumar et al., Biochemistry 2009 : There were no observed changes in secretin stimulated cAMP, intracellular calcium, ERK1/2 phosphorylation, or receptor internalization in receptor bearing COS or CHO-K1 cells in the presence or absence of exogenous RAMP transfection, although the secretin receptor trafficks normally to the cell surface in these cells in a RAMP independent manner, resulting in both free and RAMP associated receptor on the cell surface